Counseling can reduce perinatal depression risk
- Population and setting
- 2025 USPSTF draft synthesis: 21 studies, 4,974 participants with depression-status outcomes; most interventions began in pregnancy.
- What was found
- 2025 draft pooled RR 0.83 (95% CI 0.72–0.95). Relative reductions were 31% in increased-risk and 5% in lower-risk/unselected groups. Historical 2019 pooled RR: 0.61 (0.47–0.78).
- Limits and applicability
- The 2025 synthesis is a draft; the 2019 final recommendation remains listed. Endpoints include diagnosis, incidence/prevalence and screen thresholds. No estimate is a personal risk prediction or a Brighter Postpartum effect.
Sources: S02 · S03 · S61